Original researches
Effectiveness of programmed labor in patients with polymorbid conditions
Abstract
Background. Programmed labor account for about 25% of all deliveries worldwide. Modern pregnant women are increasingly affected by chronic diseases and polymorbid conditions, but data on the effectiveness of induction in this category of patients remain unstudied. The aim of
Functional state of the endometrium according to in vivo Raman spectroscopy in patients with diminished ovarian reserve: a prospective study
Abstract
Background. Diminished ovarian reserve (DOR) is recognized not only as a quantitative decline in the ovarian follicular pool but also as a manifestation of systemic reproductive aging. This process may involve the endometrium, contributing to reduced implantation potential.
Comparative evaluation of the efficacy and safety of Foley catheter preinduction versus amniotomy in patients with a uterine scar
Abstract
Background. The steadily increasing rate of cesarean sections worldwide and in Russia has led to a growing number of patients entering subsequent pregnancies with a uterine scar. Planned labor in this population is associated with limited pharmacological options due to the
Ovarian reserve in borderline and benign ovarian tumours
Abstract
Background. Borderline ovarian tumours (BOTs) and benign ovarian tumours (BeOTs) are the most common ovarian masses in reproductive-age women. Surgical treatment of BOTs is increasingly performed with preservation of reproductive function, which makes preoperative assessment
Glycemia monitoring in the prevention of complications of pregnancy in type 1 diabetes mellitus
Abstract
Diabetes mellitus (DM) in pregnant women is a global interdisciplinary problem due to serious maternal and perinatal complications. Recent publications suggest a possible reduction in adverse pregnancy outcomes when glycemia is controlled using continuous glucose monitoring
Ovarian reserve and gynecological morbidity in reproductive age: results of population-based anti-Müllerian hormone secretion study (n=351,185)
Abstract
Background. Ovarian reserve is a key parameter of reproductive prognosis. The association of individual gynecological diseases (endometriosis, uterine fibroids, pelvic inflammatory disease) and ovarian surgery with diminished ovarian reserve has been studied predominantly in
Systemic inflammation in missed abortion
Abstract
Background. A missed abortion (early pregnancy loss) (MI) is the cessation of development and death of an embryo/fetus before the 22 nd week of gestation, with the products of conception remaining in the uterine cavity (ICD-10). Most cases occur in the first trimester of
Fundamental possibilities of treatment and restoration of vaginal microbiota in vulvovaginal infections
Abstract
The treatment of vulvovaginal infections, including common dysbiotic conditions, continues to generate heated debate in the professional community. This paper examines approaches to treating non-inflammatory pathologies – in particular, bacterial vaginosis,
The effectiveness of breast cancer screening in the Moscow metropolitan area: a comparative analysis of data from women's health centers, women's consultation centers, and primary health care organizations
Abstract
Background. Breast cancer is the leading malignancy among women, and the stage at detection remains the principal determinant of prognosis. Since 2024, Women’s Health Centres (WHCs) have been established within the primary health-care network of Moscow, focusing on the
Predicting the risk of uterine fibroid recurrence after organ-preserving surgery
Abstract
Aim. To develop a prognostic calculator for the personalized assessment of the risk of uterine fibroid recurrence after organ-preserving surgical treatment in women of reproductive age. Material and methods. An observational comparative study was conducted involving 75 women
Evaluating the efficacy of transdermal estradiol for the management of early postmenopausal symptoms
Abstract
The aim of the study was to assess the efficacy, tolerability and safety of a transdermal estradiol hemihydrate spray 1.58 mg in the relief of moderate-to-severe vasomotor symptoms in early postmenopause (STRAW +10, stage +1). Material and methods. A prospective, single-arm,
Morphological features of the placenta and placental bed in obesity in patients with late reproductive losses
Abstract
Background. Late reproductive losses remain one of the relevant problems in modern obstetrics, occupying a significant place in the structure of perinatal morbidity and mortality. Obesity, accompanied by chronic inflammation, endothelial dysfunction, and oxidative stress,
Macroscopic changes in the placenta in obesity
Abstract
Background. The obesity pandemic remains a leading cause of maternal and perinatal morbidity and mortality. Obese pregnant women are at high risk of gestational diabetes mellitus (GDM) and preeclampsia (PE). The placenta, which plays a key role in the exchange between the
Luteal support to prevent early reproductive losses after in vitro fertilization in patients with severe endometriosis
Abstract
The aim of the study was to compare the effectiveness of preventing early reproductive losses in the first trimester by administering dydrogesterone for luteal support in IVF cycles in patients with severe endometriosis at a standard dose of 30 mg/day versus an investigated
Comorbidity in the thanatogenesis of maternal mortality in the Altai Krai
Abstract
Background. Despite a sustained global trend towards a reduction in maternal mortality (MM), the pace of its decline has slowed considerably over the past decade, reflecting a transformation in the aetiological structure of fatal outcomes: direct obstetric causes are being
Reviews
Incretinotherapy for obesity and hormonal contraception: working in one play
Abstract
This article describes an algorithm for choosing hormonal contraception for women with metabolic disorders and obesity undergoing incretin analogue therapy. The increasing use of these drugs, particularly glucagon-like peptide-1 receptor agonists, for the treatment of
Metabolic syndrome and endometrial hyperplasia: prediction of malignant transformation
Abstract
Atypical endometrial hyperplasia (AEH) is a precancerous condition associated with a high risk of progression to endometrioid carcinoma. Metabolic syndrome (MS) is considered one of the leading modifiable risk factors for endometrial hyperplastic disorders; however,
CLINICAL OBSERVATIONS
Comprehensive rehabilitation for vaginal relaxation syndrome associated with undifferentiated connective tissue dysplasia: a clinical observation
Abstract
Background. Vaginal relaxation syndrome (VRS) and early‑stage pelvic organ prolapse (POP) are common among women of reproductive age. Undifferentiated connective tissue dysplasia (UCTD) is considered a significant risk factor for POP and for the failure of its surgical
Favorable pregnancy outcome after late miscarriage of one of the fetuses of dichorionic twins in a woman with complete duplication of the uterus
Abstract
Background. In recent years, there has been a tendency towards an increase in the number of multiple pregnancies, which is largely associated with the wider use of assisted reproductive technologies. The course of pregnancy in such patients is associated with a significant
A rare case of bilateral pelvic masses: extragonadal localization of a benign germ cell tumor with signs of inflammation
Abstract
This clinical observation demonstrates the difficulties of diagnosing germinogenic tumors of extra-gonadal localization with ultrasound and magnetic resonance imaging (MRI) of the pelvic organs with contrast enhancement, as well as the difficulties of morphological
То practitioner’s consult
Simulation technologies in professional postgraduate training of obstetricians and gynecologists
Abstract
Background. Large-scale medical-organizational work on the implementation modern technologies into practical healthcare have improved high-tech medical care by updating the equipment inventory of medical organizations and enhancing manual skills training at all stages of
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