Topic number
4 . 2025
Reproductive health
Content
Editorial

EDITORIAL

Abstract
Original researches

Development of preeclampsia and its impact on the course of pregnancy, postpartum period and newborn

Abstract
Background. Preeclampsia (PE) is a severe complication of pregnancy, which is related to major obstetric syndromes, leading to the occurrence or exacerbation of a number of different pathological conditions during pregnancy and in the postpartum period. The aim of the study

Predictors of the effectiveness of attempted vaginal delivery in women with a scar on the uterus after cesarean section: a retrospective cohort study

Abstract
Background. Resources for conservative labor management in women with a uterine scar are underutilized. It is possible to reduce the number of emergency deliveries when attempting vaginal delivery, taking into account significant predictors. The aim of the study was to

Multivariate predictive model for gestational diabetes mellitus based on the I trimester clinical and laboratory parameters

Abstract
Background. Gestational diabetes mellitus (GDM) is a common pregnancy complication associated with risks for both mother and fetus. Early detection of GDM allows timely initiation of preventive and therapeutic measures and improvement of pregnancy outcomes. The aim of the

Iron deficiency conditions and their combined medication

Abstract
Background. About 2 billion people worldwide suffer from anemia, including 20% of non-pregnant women. The prevalence of anemia increases with age and is a socially significant problem. Combined iron fumarate preparations containing vitamins B 6 , B 9 , B 12 , vitamin C, as

Assessment of sexual dysfunction and quality of life in patients with endometriosis

Abstract
Endometriosis and infertility are urgent problems of modern gynecology, having a significant impact on the quality of life of women of reproductive age. Endometriosis is often accompanied by marked clinical manifestations: chronic pelvic pain, dysmenorrhea, dyspareunia and
Reviews

Thrombosis in the postpartum period

Abstract
Physiological changes associated with pregnancy and the postpartum period increase the risk of venous thromboembolism. VTEC (venous thromboembolic complications) can cause maternal morbidity and mortality. More than half of thrombosis is associated with thrombophilia; other

Uterine rupture during pregnancy and childbirth in women who have undergone hysteroscopic surgery: literature review

Abstract
The review analyzes and summarizes data from publications on uterine rupture during pregnancy, directly related to previous hysteroscopic operations. The modern specialized medical literature presented in the electronic database of biomedical publications PubMed from 2006 to

The role of genetics in the issues of ovarian reserve and the realization of reproductive function

Abstract
Ovarian reserve is the main quantitative and qualitative indicator of fertility of the female organism, which depends mainly on the state of genetic material and special mechanisms of its realisation. Genetic determinants concentrated in the chromosomes of human cells,

Practical aspects of using a combined oral contraceptive with estradiol valerate and dienogest: from contraception to cycle control

Abstract
Effective use of contraception requires that women make an informed choice about methods that match their individual needs and expectations. Approximately 15 years have passed since the introduction in Russia of the combined oral contraceptive with estradiol

Personalization of vitamin and mineral support for pregnant women as a strategy for preventing complications and improving perinatal outcomes

Abstract
Adequate intake of vitamins and micronutrients by women is a key factor for a healthy pregnancy and proper fetal development. Deficiencies in nutrients such as folates, iron, iodine, vitamin D, vitamin A, and omega-3 fatty acids are associated with an increased risk of
CLINICAL OBSERVATIONS

Thyroid hormone resistance syndrome and pregnancy

Abstract
Thyroid hormone resistance syndrome is a rare clinical syndrome defined by impaired sensitivity of target tissues to thyroid hormones. A clinical case of complications during pregnancy in a patient with a proven heterozygous variant of the c.947G>A p.R316H mutation of the
Practitioner's consult

Resolution following the results of the Council of Experts in the field of obstetrics-gynecology, neonatology, gastroenterology and microbiology “The impact of antibacterial therapy in gynecological practice on the microbiota of the vagina and intestines, the place of probiotics in the prevention of dysbiotic disorders”

Abstract
The XVIII Regional Scientific and Educational Forum “Mother and Child” was held in St. Petersburg from July 2 to 4, 2025. Within the framework of the forum, a council of experts was held “The impact of antibacterial therapy in gynecological practice on the
International recommendations

Uptake of orally administered tranexamic acid in women during active labor: A pilot intervention study on prophylactic treatment of postpartum hemorrhage

Abstract
Introduction. Postpartum hemorrhage is the leading cause of maternal mortality worldwide. Several studies have confirmed that tranexamic acid is effective in treating postpartum hemorrhage once started, but its prophylactic effect is under debate. As of now, most studies
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Abstract

All articles in our journal are distributed under the CC BY-NC-ND 4.0 (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International)

CHIEF EDITORS
CHIEF EDITOR
Sukhikh Gennadii Tikhonovich
Academician of the Russian Academy of Medical Sciences, V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Moscow
CHIEF EDITOR
Kurtser Mark Arkadievich
Academician of the Russian Academy of Sciences, MD, Professor, Head of the Obstetrics and Gynecology Subdepartment of the Pediatric Department, N.I. Pirogov Russian National Scientific Research Medical University, Ministry of Health of the Russian Federation
CHIEF EDITOR
Radzinsky Viktor Evseevich
Academician of the Russian Academy of Sciences, MD, Professor, Head of the Subdepartment of Obstetrics and Gynecology with a Course of Perinatology of the Medical Institute in the Russian People's Friendship University named after P. Lumumbа

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