Original researches
Severe preeclampsia and its impact on maternal mortality risk
Abstract
Severe preeclampsia (PE) is one of the leading causes of maternal mortality in the world and is included in the list of critical obstetric conditions (COC) monitored in the Russian Federation. There is conflicting information regarding the determination of the risk of
Severe preeclampsia. Clinical and anamnestic characteristics of women with induced preterm labor
Abstract
In the structure of preterm birth (PB), there is a tendency towards an increase in induced PB. Among obstetric complications requiring early delivery, hypertensive disorders, mainly severe preeclampsia, occupy a leading position. The aim of the study was to investigate
Risk factors of recurrent miscarriage
Abstract
The aim of the study was to identify clinical and anamnestic risk factors of recurrent miscarriage. Research design: open independent retrospective study was conducted. Material and methods. The study included 348 patients of reproductive age (average age – 36±3.3
Morphologic predictors of recurrent intrauterine synechiae in the reproductive age
Abstract
Intrauterine synechiae (IUS) are characterised by endometrial fibrosis and can lead to menstrual and reproductive disorders. Despite the urgency of the problem of IUS, the mechanisms of development and recurrence of the disease are poorly understood. According to the
Chronic endometritis in the pathogenesis of recurrent miscarriage
Abstract
The aim of the study was to expand the understanding of the pathogenesis of recurrent miscarriage. Study design: open independent retrospective clinical and morphological study was conducted. Material and methods. The study involved 348 patients of reproductive age (mean age
Posttransfer support for the transfer of one cryopreserved embryo at the blastocyst stage
Abstract
Background. The article presents the results of a comparative analysis of protocols for preparing the endometrium for the transfer of thawed embryos against the background of hormone replacement therapy. Aim of the study – to compare the effectiveness and safety of
Abnormal uterine bleeding in obesity in the reproductive period as a manifestation of the universal hypoxic syndrome
Abstract
The aim of the study was to study the prevalence of polymorphic variants of the VEGF-A, eNOS, IL6 and HIF-1 α genes and to determine the expression features of CD34 + and eNOS angiogenesis markers in the endometrium as manifestations of universal hypoxic syndrome in
Morphologic determinants of recurrent endometrial polyps in women of reproductive age
Abstract
Endometrial polyps are a common nosology that, although often asymptomatic, is associated with reproductive dysfunction. Hysteroresectoscopic removal of polyps is an effective treatment, but recurrence is not uncommon. The recurrence rate after polypectomy according to
Comparative characteristics of women after surgical treatment for uterine fibroids including myomectomy and hysterectomy
Abstract
The aim of the study was to clarify the factors influencing the choice of the scope of surgical treatment of uterine fibroids in women of reproductive age. Material and methods. A cross-sectional study was conducted, the medical documentation of women of reproductive age
Pathogenesis and prediction of recurrent endometrial polyps
Abstract
Endometrial polyps are a common pathology that, despite often being asymptomatic, is associated with reproductive disorders. Hysteroscopic resection of polyps is an effective treatment method, but recurrences are not uncommon. The recurrence rate after polypectomy varies
Algorithm for diagnosing and treatment for pelvic floor dysfunction
Abstract
Aim of the study was to develop and mathematically justify a therapeutic and diagnostic algorithm for the management of patients of reproductive age with pelvic floor insufficiency. Design: cohort prospective randomized comparative study. Material and methods. The study was
Psychological aspects of premature birth
Abstract
The prevalence of anxiety during pregnancy, which increases the risk of premature birth, varies from 14 to 54% in different countries. Early diagnosis of high levels of anxiety and timely psychocorrective therapy will help to avoid the development of complications of
The "Ferritin 2023" program to study population indicators of serum ferritin in women in the Moscow agglomeration (2023–2024)
Abstract
The article provides an overview of the significance of iron deficiency (ID) as a global problem, focusing on the importance and lack of study of this issue in Russian Federation, and a special role is given to describing the connection between iron deficiency and
External genital endometriosis in the pathogenesis of recurrent miscarriage
Abstract
Background. The elucidation of the mechanisms underlying recurrent pregnancy loss (RPL) in endometriosis, as well as the role of immune cells and the receptor apparatus in the disruption of immune tolerance of the mother-fetus interface, appears to be a tool for prediction
Mammary glands and combined oral contraception: a combination of esthetrol and drospirenone (сlinical trial results)
Abstract
The aim of the study was to assess the condition of the mammary glands and the quality of life of women using a combined oral contraceptive (COC) based on esthetrol and drospirenone (E4/DRSP). Material and methods. The study included 330 patients with verified benign mammary
Clinical and anamnestic features of patients with placenta accreta: analysis of risk factors and obstetric outcomes
Abstract
Placenta accreta spectrum (PAS) is a serious obstetric problem associated with high risks of maternal morbidity and mortality. The incidence of PAS is increasing worldwide, linked to the rising rates of cesarean sections and advancing maternal age. Despite previously
Therapeutic Effect and Safety of Blissel. Results of a Multicenter Open-Label Russian Observational Study (ARMOR)
Abstract
The aim of study was to evaluate the effectiveness and safety of vaginal gel containing 50 mcg of estriol for the treatment of postmenopausal vaginal mucosa atrophy, as well as to improve the quality of life of patients over the period of therapy. Materials and methods. The
Reviews
Neuropeptides in regulation of the female reproductive system functions
Abstract
This article is a review of modern literature, which reflects data on new views on the mechanisms of regulation of the hypothalamic-pituitary-ovarian axis and on the role of neuropeptides in this process, which are currently recognized as the highest level of regulation of
CLINICAL OBSERVATIONS
Formation of lactation after premature birth in patient with diabetes mellitus, rheumatoid arthritis and severe preeclampsia
Abstract
The article is devoted to the issue of supporting breastfeeding for a cohort of children especially in need – premature newborns. Prematurity, especially associated with a complicated pregnancy and surgical delivery, significantly increases the likelihood of mixed or
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