Unexpected poor response to ovarian stimulation in the in vitro fertilization program and possibilities of its overcoming
Abstract
The aim of the study was to evaluate the expediency of using the FORT (follicular output rate), FOI (follicle-to-oocyte index) and OSI (ovarian sensitivity index) indices as predictors of an unpredictable hypo-response to ovarian stimulation (OS) in the in vitro
Effectiveness of prevention and early diagnosis of critical obstetric conditions in preeclampsia as a factor in reducing maternal and infant morbidity and mortality
Abstract
The aim of the study was to assess the effectiveness of prevention and early diagnosis of critical obstetric conditions (COC) during preeclampsia in reducing maternal and infant morbidity and mortality in the perinatal center of the Western medical zone in the Khanty
Diagnosis of premature rupture of membranes in pregnant women with isthmic-cervical insufficiency using the IGFBP-1 PROM rapid test
Abstract
The efficacy evaluation of the IGFBP-1 PROM rapid test was perfomed in 157 pregnant women with symptoms and signs of premature rupture of membranes. The results obtained showed that the IGFBP-1 immunoassay has high sensitivity and specificity. The aim of the research was to
Regulation of inositol phosphate signaling pathways activity in patients with a poor ovarian response. Possibilities of adjuvant therapy
Abstract
The article provides information on inositol phosphate signaling pathways that act as key regulators of oocyte growth and maturation. The use of inositol phosphate messenger precursor molecules as a targeted adjuvant therapy in patients with poor ovarian response is
Evolution of predictive models for implementation of reproductive function in ART programs: from logistic regression to artificial intelligence
Abstract
The article presents data on the possibilities of predicting the outcomes of ART programs by building predictive models based on the literature, their evolution and current changes.
A clinical case of fertility preservation in a patient with acute myeloid leukemia
Abstract
Background. Conducting a fertility preservation program among patients with acute leukemia is extremely difficult due to severity of the condition and high risks of both thrombotic and hemorrhagic complications. Limiting the possibility of conducting a fertility preservation
Clinical observation of missed invasive cervical cancer during pregnancy
Abstract
Cervical cancer (CC) is an urgent problem in gynecological oncology, occupying a leading place among malignant neoplasms associated with pregnancy and first place among malignant neoplasms associated with pregnancy. The frequency of detection of cervical cancer according to
A clinical case of diagnosing incompetence of a uterine scar basedon ultrasound and MRI diagnostics
Abstract
The article presents a clinical case of a 33-year-old patient with a failed uterine suture, which demonstrates the difficulties in diagnosing a failed uterine scar, the effectiveness of various approaches during surgery, and a favorable outcome of pregnancy and childbirth
No additional risk of congenital anomalies after first-trimester dydrogesterone use: a systematic review and meta-analysis
Abstract
Study question. Is exposure to dydrogesterone a risk factor for congenital anomalies when given in the first trimester for recurrent/threatened pregnancy loss or as luteal support in assisted reproductive technology (ART)? Summary answer. Dydrogesterone, when given in the
Maternal obesity and the risk of postpartum infections according to mode of delivery
Abstract
The aim of the present study was to assess the impact of different maternal Body Mass Index (BMI) classes on the risk of postpartum endometritis, wound infection, and breast abscess after different modes of delivery. Secondly to estimate how the risk of postpartum infection