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1 . 2025

Targeted therapy for vulvovaginal atrophy

Abstract

The aim of the study was to determine the effectiveness of the moisturizer based on natural plant extracts and hyaluronic acid in the treatment of vulvovaginal atrophy.

Material and methods. The prospective study included data from 30 patients aged 24 to 72 years with varying degrees of vulvovaginal atrophy. All patients underwent vulvoscopy, colposcopy, vaginal pH determination, and microscopic examination of a vaginal smear for flora before and after 3 months of the gel usage. The vaginal health index, the severity of vulvovaginal atrophy symptoms using the VSQ questionnaire, and the vaginal maturation index were assessed.

Results. After a repeated study, patients using the emollient showed an improvement in their quality of life, which was assessed using the VSQ questionnaire. An objective improvement in the health of the vulvovaginal area of ​​women was also revealed according to the results of colposcopic and vulvoscopic examinations.

Conclusion. The use of the moisturizing gel Intimate Rose based on natural plant extracts and hyaluronic acid can be considered a good method of therapy and prevention of vulvovaginal atrophy. The use of this gel significantly improves the quality of life of patients with this pathology.

Keywords: vulvovaginal atrophy; genitourinary menopausal syndrome; vulvar leukoplakia; lichen sclerosus

Funding. The study had no sponsor support.

Conflict of interest. The authors declare no conflict of interest.

For citation: Vinogradova O.P., Shtakh A.F., Bocharnikov D.Yu., Biryuchkova O.A., Mikhailova N.A., Karaseva M.S. Targeted therapy for vulvovaginal atrophy. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2025; 13 (1); 72–7. DOI: https://doi.org/10.33029/2303-9698-2025-13-1-72-77 (in Russian)

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CHIEF EDITORS
CHIEF EDITOR
Sukhikh Gennadii Tikhonovich
Academician of the Russian Academy of Medical Sciences, V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Moscow
CHIEF EDITOR
Kurtser Mark Arkadievich
Academician of the Russian Academy of Sciences, MD, Professor, Head of the Obstetrics and Gynecology Subdepartment of the Pediatric Department, N.I. Pirogov Russian National Scientific Research Medical University, Ministry of Health of the Russian Federation
CHIEF EDITOR
Radzinsky Viktor Evseevich
Corresponding Member of the Russian Academy of Sciences, MD, Professor, Head of the Subdepartment of Obstetrics and Gynecology with a Course of Perinatology of the Medical Institute in the Russian People?s Friendship University named after P. Lumumbа
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