First study of using fluorescent visualization of deep infiltrative endometriosis in laparoscopy

• Alla K. Politova
• Mariya I. Rokhlina
• Elena V. Rokhlina
• Valentina V. Titova
• Kseniya Yu. Viazmina

Abstract

This study describes the first experience of using intraoperative fluorescent visualization of the surgical field during endoscopic surgical treatment of patients with deep infiltrative endometriosis in order to objectify the boundaries of the abnormal focus and increase the radicality of surgical treatment. It is known that the gold standard for diagnosis and treatment of external genital endometriosis is laparoscopy. However, even in this case, assessing the depth of invasion of the nodule is difficult. Near-infrared fluorescence navigation using indocyanine green has the potential to assist surgeons in the endoscopic treatment of extensive forms of external genital endometriosis.

Keywords: deep infiltrative endometriosis; indocyanine green; fluorescent visualization; laparoscopy

References

1. Tskhay V.B., Khudyakov A., Terjung A., Polstyanoy A.M., von Westernhagen M., Avazashvili Z., et al. Deep infiltrating endometriosis with bowel involvement. Literature review. Sibirskoe meditsinskoe obozrenie [Siberian Medical Review]. 2021; (2): 5–11. DOI: https://doi.org/10.20333/2500136-2021-2-5-11 (in Russian)

2. Popov A.A., Puchkov K.V., Fedorov A.A., Fedotova I.S., Tyurina S.S. Surgical treatment of patients with colorectal endometriosis: anatomical features, indications, surgical technique, complications. Rossiyskiy vestnik akushera-ginecologa [Russian Bulletin of Obstetrician-Gynecologist]. 2020; 20 (2): 95–104. DOI: https://doi.org/10.17116/rosakush20202002195 (in Russian)

3. Koninckx P.R., Martin D.C. Deep endometriosis: a consequence of infiltration or retraction or possibly adenomyosis externa? Fertil Steril. 1992; 58 (5): 924–8. DOI: https://doi.org/10.1016/s0015-0282(16)55436-3 PMID: 1426377.

4. Shchukina N.A., Buyanova S.N. Modern view on the diagnosis and treatment of endometriosis. Rossiyskiy meditsinskiy zhurnal [Russian Medical Journal]. 2014; (14): 1002–5. (in Russian)

5. Araujo S.E., Seid V.E., Marques R.M., Gomes M.T. Advantages of the robotic approach to deep infiltrating rectal endometriosis: because less is more. J Robot Surg. 2016; 10 (2): 165–9. DOI: https://doi.org/10.1007/s11701-016-0586-8 Epub 2016 Apr 12. PMID: 27072152.

6. Alander J.T., Kaartinen I., Laakso A., Pätilä T., Spillmann T., Tuchin V.V., et al. A review of indocyanine green fluorescent imaging in surgery. Int J Biomed Imaging. 2012; 2012: 940585. DOI: https://doi.org/10.1155/2012/940585 Epub 2012 Apr 22. PMID: 22577366; PMCID: PMC3346977.

7. Reinhart M.B., Huntington C.R., Blair L.J., Heniford B.T., Augenstein V.A. Indocyanine green: historical context, current applications, and future considerations. Surg Innov. 2016; 23 (2): 166–75. DOI: https://doi.org/10.1177/1553350615604053 Epub 2015 Sep 10. PMID: 26359355.

8. Izrailov R.E., Mukhaev I.R., Semenov N.E., Matveychuk D.A., Andrianov A.V. Indocyanine green in diagnostics and management of gastric cancer. Kremlevskaya meditsina. Klinicheskiy vestnik [Kremlin Medicine. Clinical Bulletin]. 2023; (4): 49–52. (in Russian)

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)