Risk factors of recurrent miscarriage
AbstractThe aim of the study was to identify clinical and anamnestic risk factors of recurrent miscarriage.
Research design: open independent retrospective study was conducted.
Material and methods. The study included 348 patients of reproductive age (average age – 36±3.3 years). The patients of the studied cohort were stratified into 2 groups: the main one (n=230) – with a verified diagnosis of recurrent miscarriage, having a history of ≥2 pregnancy losses, and the comparison group (n=118), which included women with realized fertility.
Results. Significant (p<0.05) clinical and anamnestic risk factors for recurrent miscarriage were: age over 35 years (OR 1.15; 95% CI 1.097–1.22), obesity (OR 10.7; 95% CI 2.36–48.7), chronic anemia (OR 5.7; 95% CI 2.61–12.96), (OR 4.0; 95% CI 1.30–12.84), low body mass index (OR 4.5; 95% CI 1.60–13.06).
Conclusion. Rational consideration of these factors determines the direction of preventive measures in women at risk in order to improve reproductive outcomes.
Keywords: recurrent miscarriage; risk factors; anemia; hypothyroidism;
obesity
Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Mikhalev S.A., Radzinskiy V.E., Masalimova D.N. Risk factors of recurrent miscarriage. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2024; 12 (3): 20–5. DOI: https://doi.org/10.33029/2303-9698-2024-12-3-20-25 (in Russian)
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