Severe preeclampsia. Clinical and anamnestic characteristics of women with induced preterm labor

• Alina V. Solovieva
• Maria A. Spitsyna
• Olga K. Doronina
• Ekaterina Yu. Aleynikova

Abstract

In the structure of preterm birth (PB), there is a tendency towards an increase in induced PB. Among obstetric complications requiring early delivery, hypertensive disorders, mainly severe preeclampsia, occupy a leading position.

The aim of the study was to investigate clinical and anamnestic characteristics of women with induced preterm labor due to severe preeclampsia.

Material and methods. A retrospective case-control study included 122 women. Depending on the period of manifestation of severe PE, group 1 included women with induced premature birth for early PE with severe course up to 33⁶ weeks of gestation (n=50), group 2 included women with induced premature birth for late PE with severe course from 34 to 36⁶ weeks of gestation (n=42), group 3 includes healthy women with a physiological course of pregnancy who gave birth to full-term live children (n=30).

Results. Pregestational overweight and obesity, chronic arterial hypertension, varicose veins of the lower extremities, a high individual risk of developing PE and fetal growth retardation according to the results of prenatal screening of the I trimester, debut of gestational (pregnancy-induced) hypertension in the II trimester are risk factors for the development of early PE with severe course. The age of a woman over 35 years old, a history of preeclampsia, late first appearance in the antenatal clinic and the onset of gestational (pregnancy-induced) hypertension in the III trimester are risk factors for the development of late PE with a severe course.

Keywords: early severe preeclampsia; late severe preeclampsia; risk factors; induced preterm birth

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