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Спецвыпуск . 2024

Prediction of late preterm spontaneous delivery

Abstract

The problem of late premature labor occupies a leading position in modern obstetrics and perinatology. Currently, there is no single opinion and no identical approaches in predicting late premature spontaneous labor. This prevents the creation of a single algorithm of actions to prevent them. The article presents up-to-date information on the serum marker proteins, as well as highlights some aspects of the pathogenesis of premature labor on the model of fetoplacental homeostasis disorders.

Keywords:late premature spontaneous labor; placental insufficiency, marker serum proteins; pregnancy-associated plasma protein-A (PAPP-A); placental growth factor (PlGF); soluble fms-like tyrosine kinase-1 (sFlt-1)

Funding. The study had no sponsor support.

Conflict of interest. The authors declare no conflict of interest.

Contribution. All the authors made a significant contribution to the preparation of the article, read and approved the final version before publication. Special contribution: manuscript preparation, analytical processing of the text, approval of the manuscript for publication – Apresyan S.V.; thematic publications search and reviewing, processing and writing the text of the manuscript, analytical processing of the text – Zyukina Z.V.; thematic publications search – Kushkhatueva L.B.

For citation: Apresyan S.V., Zyukina Z.V., Kushkhatueva L.B. Prediction of late preterm spontaneous delivery. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2024; 12. Supplement: 105–10. DOI: https://doi.org/10.33029/2303-9698-2024-12-suppl-105-110 (in Russian)



REFERENCES

1. WHO recommendations for care of the preterm or low birth weight infant. Geneva: World Health Organization, 2022. License: CC BY-NC-SA 3.0 IGO. URL: https://www.who.int/news-room/events/detail/2022/11/17/default-calendar/launch-of-the-who-recommendations-for-care-of-the-preterm-or-low-birth-weight-infant

2. Fente B.M., Asaye M.M., Tesema G.A., Gudayu T.W. Development and validation of a prognosis risk score model for preterm birth among pregnant women who had antenatal care visit, Northwest, Ethiopia, retrospective follow-up study. BMC Pregnancy Childbirth. 2023; 23 (1): 732. DOI: https://doi.org/10.1186/s12884-023-06018-1

3. Ageeva L.I., Aleksandrova G.A., Golubev N.A., Kirillova G.N., Ogryzko E.V., Os’kov Yu.I., et al. Healthcare in Russia. 2021: statistical compendium. In: Rosstat. Мoscow, 2021: 171 p. (in Russian)

4. Predictive obstetrics. In: V.E. Radzinsky, S.A. Knyazev, I.N. Kostin (eds). Moscow: Redaktsiya zhurnala StatusPraesens, 2021: 520 p. (in Russian)

5. Peter S., Peter S. Preterm birth. Int J Sci Res. (IJSR). 2021; 10 (7). DOI: https://doi.org/10.36106/ijsr/5402527

6. Paquette A.G., MacDonald J., Bammler T., Day D.B., Loftus C.T., Buth E., et al. Placental transcriptomic signatures of spontaneous preterm birth. Am J Obstet Gynecol. 2023; 228 (1): 73.e1–18. DOI: https://doi.org/10.1016/j.ajog.2022.07.015

7. Karavaeva A.L., Timofeeva L.A., Tsechoeva T.K., Tyutyunnik V.L., Kan N.E., Zubkov V.V. Late premature newborns in increased attention. Literature review. Part 2. Features of the morbidity of late premature newborns. Neonatologiya: novosti, mneniya, obuchenie [Neonatology: News, Opinions, Training]. 2023; 11 (1): 65–75. DOI: https://doi.org/10.33029/2308-2402-2023-11-1-65-75 (in Russian)

8. Karavaeva A.L., Timofeeva L.A., Zubkov V.V., Tyutyunnik V.L., Kan N.E., Tubylova O.N. Late premature newborns in increased attention. Literature review. Part 1. Discussions on prolongation of pregnancy and the expediency of antenatal prevention of distress syndrome in late pregnancy. Neonatologiya: novosti, mneniya, obuchenie [Neonatology: News, Opinions, Training]. 2022; Vol. 10 (2): 55–62. DOI: https://doi.org/10.33029/2308-2402-2022-10-3-55-62 (in Russian)

9. URL: https://www.who.int/ru/news-room/fact-sheets/detail/preterm-birth

10. World Health Organization, WHO Library Cataloguing-in-Publication. WHO recommendations on interventions to improve preterm birth outcomes. 2015: 98 p. URL: https://apps.who.int/iris/bitstream/handle/10665/183037/9789241508988_eng.pdf?sequence=1

11. American College of Obstetricians and Gynecologists’ Committee on Obstetric Practice, Society for Maternal-Fetal Medicine. Medically indicated late-preterm and early-term deliveries: ACOG Committee Opinion, Number 831. Obstet Gynecol. 2021; 138 (1): e35–9. DOI: https://doi.org/10.1097/AOG.0000000000004447

12. Radzinsky V.E., Orazmuradov A.A. Premature birth is an unsolved problem of the XXI century. Rossiyskaya detskaya oftal’mologiya [Russian Pediatric Ophthalmology]. 2021; (3): 9–16. DOI: https://doi.org/10.25276/2307-6658-2021-3-9-16 (in Russian)

13. Makarentseva A.O. Achievements of perinatal reform and reserves for further reduction of infant mortality in Russia. Demograficheskoe obozrenie [Demographic Overview]. 2023; 10 (3): 62–81. DOI: https://doi.org/10.17323/demreview.v10i3.17970 (in Russian)

14. Kim J.I. Development and validation of the 23-item preterm birth risk assessment scale-Korean version. BMC Pregnancy Childbirth. 2023; 23 (1): 668. DOI: https://doi.org/10.1186/s12884-023-05975-x

15. Radzinsky V.E., Fuks A.M. (eds). Obstetrics. A guide to practical exercises. Textbook. 6th ed., revised and additional. Moscow: GEOTAR-Media, 2021: 736 p. DOI: https://doi.org/10.33029/9704-6029-0-OBS-2020-1-736 (in Russian)

16. Obidova V.L. Features of the fetoplacental system in preterm labor (literature review). Ekonomika i sotsium [Economy and Society]. 2023; 107 (4): 438–44. (in Russian)

17. The Russian Society of Obstetricians and Gynecologists (ROAG). Clinical recommendations «Normal pregnancy». 2020. (in Russian)

18. Alldred S.K., Takwoingi Y., Guo B., Pennant M., Deeks J.J., Neilson J.P., et al. First and second trimester serum tests with and without first trimester ultrasound tests for Down’s syndrome screening. Cochrane Database Syst Rev. 2017; 3: CD012599. DOI: https://doi.org/10.1002/14651858.CD012599

19. Order of the Ministry of Health of the Russian Federation dated 20.10.2020 No. 1130n «On approval of the Procedure for providing medical care in the field of “Obstetrics and Gynecology”». (in Russian)

20. Tsibizova V.I., Govorov I.E., Pervunina T.M., Komlichenko E.V., Kudryashova E.K., Blinov D.V., et al. Prenatal screening of the first trimester in multiple pregnancies. Part I: comparative analysis of serum PAPP-A and β-HCG proteins in pregnancy that occurred spontaneously or as a result of in vitro fertilization. Akusherstvo, ginekologiya, reproduktologiya [Obstetrics, Gynecology, Reproductology]. 2020; Vol. 14 (1): 25–33. DOI: https://doi.org/10.17749/2313-7347.2020.14.1.25-33 (in Russian)

21. Markelova A.N., Muradyan M.M., Pavlenko K.I. Assessment of the possibility of using biochemical screening indicators to diagnose the development of pregnancy complications. In: VII Mezhdunarodnaya nauchnaya konferentsiya «Aktual’nye problemy meditsinskoy nauki i obrazovaniya (APMNO-2019)»: sbornik statey [VII International Scientific Conference «Actual Problems of Medical Science and Education (APMSE-2019)»: collection of articles]. Penza: Izdatel’stvo PGU, 2019: 309–13. (in Russian)

22. Ryabova E.S., Badalova L.M. The level of PAPP-A in the first trimester and the outcome of pregnancy in first-time mothers. Vestnik novykh meditsinskikh tekhnologiy [Bulletin of New Medical Technologies]. 2017; 24 (4): 131–6. DOI: https://doi.org/10.12737/article_5a38fa22b94109.69590302 (in Russian)

23. Medvedev M.V., Altynnik N.A., Knyazev P.V. Exchange of experience. Prognosis and prevention of preeclampsia and fetal growth retardation at 11–14 weeks of pregnancy: analysis of 1001 observations. Prenatal’naya diagnostika [Prenatal Diagnosis]. 2018; 17 (3): 261–6. (in Russian)

24. Kuchukova O.I., Tsibizova V.I., Pervunina T.M. Biochemical markers of the first trimester in the prediction of obstetric complications. Rossiyskiy zhurnal personalizirovannoy meditsiny [Russian Journal of Personalized Medicine]. 2023; 3 (2): 93–7. DOI: https://doi.org/10.18705/2782-3806-2023-3-2-93-97 (in Russian)

25. Cherepanova N.A., Zamaleeva R.S., Mal’tseva L.I., Frizina A.V., Lazareva V.K., Zefirova T.P., Zhelezova M.E., et al. New possibilities for predicting fetal development delay in women. Prakticheskaya meditsina [Practical Medicine]. 2016; 93 (1): 63–7. (in Russian)

26. Prasad P., Romero R., Chaiworapongsa T., Gomez-Lopez N., Lo A., Galaz J., et al. Further evidence that an episode of premature labor is a pathologic state: involvement of the insulin-like growth factor system. Fetal Diagn Ther. 2023; 50 (4): 236–47. DOI: https://doi.org/10.1159/000530862

27. Paules C., Pueyo V., Martí E., de Vilchez S., Burd I., Calvo P., et al. Threatened preterm labor is a risk factor for impaired cognitive development in early childhood. Am J Obstet Gynecol. 2017; 216 (2): 157.e1–7. DOI: https://doi.org/10.1016/j.ajog.2016.10.022

28. Navalón P., Ghosn F., Ferrín M., Almansa B., Moreno-Giménez A., Campos-Berga L., et al. Are infants born after an episode of suspected preterm labor at risk of attention deficit hyperactivity disorder? A 30-month follow-up study. Am J Obstet Gynecol. 2022; 227 (5): 757.e1–11. DOI: https://doi.org/10.1016/j.ajog.2022.05.065

29. Ghosn F., Navalón P., Pina-Camacho L., Almansa B., Sahuquillo-Leal R., Moreno-Giménez A., et al. Early signs of autism in infants whose mothers suffered from a threatened preterm labor: a 30-month prospective follow-up study. Eur Child Adolesc Psychiatry. 2022; 31 (7): 1–13. DOI: https://doi.org/10.1007/s00787-021-01749-y

30. Jaiman S., Romero R., Pacora P., Erez O., Jung E., Tarca A.L., et al. Disorders of placental villous maturation are present in one-third of cases with spontaneous preterm labor. J Perinat Med. 2021; 49 (4): 412–30. DOI: https://doi.org/10.1515/jpm-2020-0138

31. Visser L., van Buggenum H., van der Voorn J.P., Heestermans L., Hollander K.W.P., Wouters M., et al. Maternal vascular malperfusion in spontaneous preterm birth placentas related to clinical outcome of subsequent pregnancy. J Matern Fetal Neonatal Med. 2021; 34 (17): 2759–64. DOI: https://doi.org/10.1080/14767058.2019.1670811

32. Giorgione V., Quintero Mendez O., Pinas A., Ansley W., Thilaganathan B. Routine first-trimester pre-eclampsia screening and risk of preterm birth. Ultrasound Obstet Gynecol. 2022; 60 (2): 185–91. DOI: https://doi.org/10.1002/uog.24915

33. Chiu C.P.H., Feng Q., Chaemsaithong P., Sahota D.S., Lau Y.Y., Yeung Y.K., et al. Prediction of spontaneous preterm birth and preterm prelabor rupture of membranes using maternal factors, obstetric history and biomarkers of placental function at 11–13 weeks. Ultrasound Obstet Gynecol. 2022; 60 (2): 192–9. DOI: https://doi.org/10.1002/uog.24917

34. Rode L., Wulff C.B., Ekelund C.K., Hoseth E., Petersen O.B., Tabor A., et al. First-trimester prediction of preterm prelabor rupture of membranes incorporating cervical length measurement. Eur J Obstet Gynecol Reprod Biol. 2023; 284: 76–81. DOI: https://doi.org/10.1016/j.ejogrb.2023.03.003

35. Wu W.B., Xu Y.Y., Cheng W.W., Yuan B., Zhao J.R., Wang Y.L., et al. Decreased PGF may contribute to trophoblast dysfunction in fetal growth restriction. Reproduction. 2017; 154 (3): 319–29. DOI: https://doi.org/10.1530/REP-17-0253

36. Muttukrishna S., Swer M., Suri S., Jamil A., Calleja-Agius J., Gangooly S., et al. Soluble flt-1 and PlGF: new markers of early pregnancy loss? PLoS One. 2011; 6 (3): e18041. DOI: https://doi.org/10.1371/journal.pone.0018041

37. Miyake T., Kumasawa K., Sato N., Takiuchi T., Nakamura H., Kimura T. Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells. Sci Rep. 2016; 6: 24853. DOI: https://doi.org/10.1038/srep24853

38. Hussein S., Ju W., Pizzella S., Flory M., Chu C., Wang Y., et al. Reduced expression in preterm birth of sFLT-1 and PlGF with a high sFLT-1/PlGF ratio in extracellular vesicles suggests a potential biomarker. Front Endocrinol. 2022; 13: 1024587. DOI: https://doi.org/10.3389/fendo.2022.1024587

39. Stepan H., Galindo A., Hund M., Schlembach D., Sillman J., Surbek D., et al. Clinical utility of sFlt-1 and PlGF in screening, prediction, diagnosis and monitoring of pre-eclampsia and fetal growth restriction. Ultrasound Obstet Gynecol. 2023; 61 (2): 168–80. DOI: https://doi.org/10.1002/uog.26032

40. Garcia-Manau P., Bonacina E., Serrano B., Caamiña S., Ricart M., Lopez-Quesada E., et al. Clinical effectiveness of routine first-trimester combined screening for pre-eclampsia in Spain with the addition of placental growth factor. Acta Obstet Gynecol Scand. 2023; 102 (12): 1711–8. DOI: https://doi.org/10.1111/aogs.14687

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CHIEF EDITORS
CHIEF EDITOR
Sukhikh Gennadii Tikhonovich
Academician of the Russian Academy of Medical Sciences, V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Moscow
CHIEF EDITOR
Kurtser Mark Arkadievich
Academician of the Russian Academy of Sciences, MD, Professor, Head of the Obstetrics and Gynecology Subdepartment of the Pediatric Department, N.I. Pirogov Russian National Scientific Research Medical University, Ministry of Health of the Russian Federation
CHIEF EDITOR
Radzinsky Viktor Evseevich
Corresponding Member of the Russian Academy of Sciences, MD, Professor, Head of the Subdepartment of Obstetrics and Gynecology with a Course of Perinatology of the Medical Department in the Russian People?s Friendship University

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