To the content
2 . 2023

A singlecenter retrospective safety study of myomectomy during caesarean section

Abstract

Abstract

The need of myomectomy during cesarean section is contraversive because it can be associated with high risk of haemorrhage, blood transfusions and surgical complications. At the same time, a number of studies demonstrate the safety of simultaneous caesarean section with fibroid enucleation.

A retrospective analysis of 120 operations performed for 2020–2022 in obstetric department of the Moscow City Clinical Hospital 52. We investigate the effectiveness and safety of myomectomy during caesarean section, features of surgical operation, the probability of complications. The patients were divided into three groups. In the first group, cesarean section was combined with myomectomy, in the second group, uterine fibroid remained intact, and in patients of the third group, myoma were not detected, performed cesarean section.

The study demonstrated the absence of significant differences in the first and second groups in the frequency of complications and the need of blood transfusion, as well as the hemoglobin level after surgical treatment (p>0.05). Considering that the average age of the patients was 35.2±5.3 years, the simultaneous operation allows to shorten the interpregnancy interval with no serious complications due to simultaneous caesarean section with myomectomy.

Keywords:caesarean section; myomectomy; uterine fibroids; complications; simultaneous operation

Funding. The study had no sponsor support.

Conflict of interest. The authors declare no conflict of interest.

Contribution. Concept and design of the study – Korennaya V.V., Grabovsky V.M.; article writing and statistical processing – Markina K.N.; editing – Lysenko M.A., Kokaya I.Yu.; collection and analysis of material – Markina K.N., Grabovsky V.M., Kokaya I.Yu.

For citation: Markina K.N., Grabovsky V.M., Kokaya I.Yu., Korennaya V.V., Lysenko M.A. A singlecenter retrospective safety study of myomectomy during caesarean section. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2023; 11 (2): 6–12. DOI: https://doi.org/10.33029/2303-9698-2023-11-2-6-12 (in Russian)

References

1. Qidwai G.I., Caughey A.B., Jacoby A.F. Obstetric outcomes in women with sonographically identifed uterine leiomyomata. Obstet Gynecol. 2006; 107 (2 pt 1): 376–82.

2. Klatsky P.C., Tran N.D., Caughey A.B., Fujimoto V.Y. Fibroids and reproductive outcomes: a systematic literature review from conception to delivery. Am J Obstet Gynecol. 2008; 198 (4): 357–66.

3. Kolankaya A., Arici A. Myomas and assisted reproductive technologies: when and how to act? Obstet Gynecol Clin North Am. 2006; 33 (1): 145–52.

4. Lam S.-J., Best S., Kumar S. The impact of fibroid characteristics on pregnancy outcome. Am J Obstet Gynecol. 2014; 211 (4): 395. DOI: https://doi.org/10.1016/j.ajog.2014.03.066

5. Stout M.J., Odibo A.O., Graseck A.S., MacOnes G.A., Crane J.P., Cahill A.G. Leiomyomas at routine second-trimester ultrasound examination and adverse obstetric outcomes. Obstet Gynecol. 2010; 116 (5): 1056–63.

6. Guler A.E., Guler Z.C.D., Kinci M.F., Mungan M.T. Myomectomy during cesarean section: why do we abstain from? J Obstet Gynecol India 2020; 70: 133–7. DOI: https://doi.org/10.1007/s13224-019-01303-6

7. Pergialiotis V., Sinanidis I., Louloudis I.-E., Vichos T., Perrea D.N., Doumouchtsis S.K. Perioperative complications of cesarean delivery myomectomy: a meta-analysis. Obstet Gynecol. 2017; 130 (6): 1295–303.

8. Turgal M., Ozgu-Erdinc A.S., Beksac K., Ozyuncu O., Karaagaoglu E., Beksac M.S. Myomectomy during cesarean section and adhesion formation as a long-term postoperative complication. Ginekol Pol. 2015; 86 (6): 457–60.

9. Kathpalia S.K., Arora D., Vasudeva S., Singh S. Myomectomy at cesarean section: a safe option. Med J Armed Forces India. 2016; 72: 161–3.

10. Topcu H.O., Iskender C.T., Timur H., Kaymak O., Memur T., Danisman N. Outcomes after cesarean myomectomy versus cesarean alone among pregnant women with uterine leiomyomas. Int J Gynecol Obstet. 2015; 130 (3): 244–6. DOI: https://doi.org/10.1016/j.ijgo.2015.03.035

11. Sparic R., Malvasi A., Kadija S., Stefanovic A., Radjenovic S.S., Popovic J., et al. Safety of cesarean myomectomy in women with single anterior wall and lower uterine segment myomas. J. Matern Fetal Neonatal Med. 2018; 31 (15): 1972–5. DOI: https://doi.org/10.1080/14767058.2017.1333096

12. Zhao R., Wang X., Zou L., Zhang W. Outcomes of myomectomy at the time of cesarean section among pregnant women with uterine fibroids: a retrospective cohort study. Biomed Res Int. 2019; 2019: 7576934. DOI: https://doi.org/10.1155/2019/7576934

13. Garg P., Bansal R. Cesarean myomectomy: a case report and review of the literature. J Med Case Rep. 2021; 15 (1): 193. DOI: https://doi.org/10.1186/s13256-021-02785-7

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITORS
CHIEF EDITOR
Sukhikh Gennadii Tikhonovich
Academician of the Russian Academy of Medical Sciences, V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Moscow
CHIEF EDITOR
Kurtser Mark Arkadievich
Academician of the Russian Academy of Sciences, MD, Professor, Head of the Obstetrics and Gynecology Subdepartment of the Pediatric Department, N.I. Pirogov Russian National Scientific Research Medical University, Ministry of Health of the Russian Federation
CHIEF EDITOR
Radzinsky Viktor Evseevich
Corresponding Member of the Russian Academy of Sciences, MD, Professor, Head of the Subdepartment of Obstetrics and Gynecology with a Course of Perinatology of the Medical Department in the Russian People?s Friendship University

Journals of «GEOTAR-Media»