Early prognosis of preeclampsia: the reality of today
AbstractBackground. Researchers are looking for the most optimal predictive markers of preeclamsia. First of all, this is due to the possibility of timely prevention of preeclampsia and proper perinatal observation. The search of the most important markers of preeclampsia was the main task of this review.
The aim of this work was to identify the most ideal tools for prognosis of preeclampsia.
Material and methods. We searched for publications for the period 1963–2021 using the terms "preeclampsia", "gestational hypertension".
Results. Our search made it possible to identify and analyze 154 scientific publications.
Conclusion. The combination of several markers can provide the best predictive accuracy to detect preeclampsia. To select ideal markers, it is necessary to conduct a multicenter prospective study.
Keywords:preeclampsia; biomarkers; predictors of maternal and fetal complications
Contribution. Concept development: idea formation, formulation and development of key goals and objectives – Andreeva M.D., Karakhalis L.Yu.; development of design and methodology – Andreeva M.D., Balayan I.S., Karakhalis L.Yu.; conducting a study – analysis and interpretation of the data obtained – Andreeva M.D., Karakhalis L.Yu.; preparation and editing of the text: drafting the manuscript; participation in scientific design – Balayan I.S.; preparation and editing of the text – critical revision of the manuscript with the introduction of a valuable comment of intellectual content – Andreeva M.D., Karakhalis L.Yu.; approval of the final version of the article – taking responsibility for all aspects of the work, the integrity of all parts of the article and its final version – Andreeva M.D., Balayan I.S., Karakhalis L.Yu.
Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Andreeva M.D., Balayan I.S., Karakhalis L.Yu. Early prognosis of preeclampsia: the reality of today. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2023; 11 (1): 19–27. DOI: https://doi.org/10.33029/2303-9698-2023-11-1-19-27 (in Russian)