Legal and medical issues of labor induction

• Sergey A. Knyazev
• Oleg B. Nevzorov
• Natalia A. Sementsova
• Marina A. Tsarkova

AbstractThe problem of labor induction has a set of not only medical issues, but also legal ones. The nuances of clinical situations when this or that method is contraindicated, the lack of registration in the Russian Federation for some products used in the world, the small domestic market of pharmacological substances, the narrowness of the legal field for the use of induction agents in premature or post-term pregnancy - all these problems require the expansion of existing boundaries for optimization work, as well as the entry of new products to the market of medical devices.

Keywords:labor induction; post-term pregnancy; preterm pregnancy

REFERENCES

1. Churchill F. A practical guide to the study of women’s diseases / Compositions of F. Churchill, professor of obstetrics: trans. from English. 5th ed. Issue 4 Moscow: A.I. Mamontov, 1879 (in Russian)

2. Cook J.W. Man-Midwife, Male Feminist: The Life and Times of George Macaulay, M.D., Ph.D. (1716–1766). Michigan Publishing, University of Michigan Library, 2006.

3. Brown K. Guide to obstetrics. Saint Petersburg, 1860. (in Russian)

4. Krassovsky A.Ya. Operative obstetrics with the inclusion of the doctrine of the irregularities of the female pelvis. Saint Petersburg, 1885. (in Russian)

5. Kolosov M. Operative obstetrics. Moscow: Gosudarstvennoe meditsinskoe izdatel’stvo, 1929. (in Russian)

6. 6. Clinical guidelines «Unsuccessful attempt to induce labor (preparation of the cervix for childbirth and labor induction)», year of approval of the ROAG: 2021. (in Russian)

7. Order of the Ministry of Health of Russia dated February 28, 2019 No. 103n (as amended on June 23, 2020) “On approval of the procedure and terms for the development of clinical recommendations, their revision, the standard form of clinical recommendations and the requirements for their structure, composition and scientific validity included in clinical information recommendations. (in Russian)

8. Williams M.C., et al. Dose variation that is associated with approximated onequarter tablet doses of misoprostol. Am J Obstet Gynecol. 2002; 187 (3): 615–9.

9. URL: https://www.dggg.de/presse-news/pressemitteilungen/mitteilung/rotehand-brief-zu-cytotec-r-ist-konsequent-und-richtig-1191/

10. URL: https://www.sggg.ch/fileadmin/user_upload/63_Misoprostol_zur_Ge-burtseinleitung.pdf

11. The Editors of The Lancet. Retraction and republication - misoprostol drug to be withdrawn from French market. Lancet. 2017; 390 (10 110): e41.

12. URL: https://docetp.mpa.se/LMF/Misodel%20vaginal%20delivery%20system%20ENG%20PL_09001be6803f765b.pdf

13. URL: https://www.deutsche-apotheker-zeitung.de/news/artikel/2021/09/02/misoprostol-in-angusta-orales-arzneimittel-zur-geburtseinleitung-endlich-auf-dem-deutschen-markt

14. URL: https://www.medicines.org.uk/emc/product/3436/smpc

15. Zhang Y., Wang F. Carbohydrate drugs: current status and development prospect. Drug Discov Ther. 2015; 9 (2): 79-87.

16. Ashwal E., et al. Pre-induction cervical ripening: comparing between two vaginal preparations of dinoprostone in women with an unfavorable cervix. J Matern Fetal Neonatal Med. 2014; 27 (18): 1874-9.

17. Kovacs L., et al. Termination of very early pregnancy by RU 486 - an antiprogestational compound. Contraception. 1984; 29 (5): 399-410.

18. Bygdeman M., Swahn M.L. Uterine contractility during pregnancy and the effect of abortifacient drugs. Baillieres Clin Obstet Gynaecol. 1990; 4 (2): 249-61.

19. Birgerson L., Odlind V. Early pregnancy termination with antiprogestins: a comparative clinical study of RU 486 given in two dose regimens and Epostane. Fertil Steril. 1987; 48 (4): 565-70.

20. URL: https://www.aims.org.uk/journal/item/misoprostol-cytotec

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)