Noninvasive methods of therapy for human papillomavirus infection in patients with cervical intraepithelial neoplasia: a systematic review and metaanalysis
AbstractIn the article an overview of the study to assess the effectiveness of noninvasive methods of therapy for human papillomavirus infection in patients with cervical intraepithelial neoplasia, which led to a statistically significant increase in frequency of HPV elimination compared to the control group data, is represented.
It was found that treatment of biological and herbal regimen, interferon regimen and probiotics benefit patients who have HPV infection and low-grade squamous intraepithelial cervical lesion. Both clearance of HPV and regression of cervical lesions were significant. However, more studies with less heterogeneity are needed to draw a concrete conclusion.
Keywords:cervical lesion, herb, human papillomavirus, interferon, probiotics
Funding. The authors received no financial support.
Conflict of interests. The authors declare no conflict of interests.
For citation: Baranov 1.1., Zarochentseva N.V., Malinovskaya V.V., Vyzhlova E.N. Noninvasive methods of therapy for human papillomavirus infection in patients with cervical intraepithelial neoplasia: a systematic review and metaanalysis. Akusher-stvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2021; 9 (1): 31-43. DOI: https://doi.org/10.33029/2303-9698-2021-9-1-31-43 (in Russian)
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