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3. Приложение . 2020

Gestational diabetes mellitus and anaemia: the contraversions of pathogenesis

Abstract

Aim – to systematize data on the gestational diabetes mellitus (GDM) and anemia pathogenesis, available in the scientific literature.

Material and methods. The review includes PubMed, Medline and Scopus publications over the past 10 years, which observe aspects of gestational diabetes and anemia pathogenesis

Results. An analytical review on the problem of GDM and its complications for mother and child is presented. The pathogenetic relationship between anemia and GDM is shown; the main links in the pathogenesis of GDM are described, as well as the effect of GDM on epigenetic programming of the fetus.

Conclusions. Anemia appears as a predictor of GDM and is pathogenetically linked to it through the complicated biochemical changes both in mother and fetus. Modification of antenatal follow-up and preconception care models in accordance to clinical guidelines is crucially important in prevention of GDM and anemia development.

Keywords:gestational diabetes mellitus (GDM), anemia, pathogenesis of GDM, epigenetics, oxidative stress, preconception care

Funding. The study had no sponsor support.

Conflict of interests. The authors declare no conflict of interests.

For citation: Epishkina-Minina A.A., Khamoshina M.B., Startseva N.M., Damirova S.F., Zyukina Z.V., Anikeev A.S. Gestational diabetes mellitus and anaemia: the contraversions of pathogenesis. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2020; 8 (3). Supplement: 86-93. DOI: 10.24411/2303-9698-2020-13914 (in Russian)

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CHIEF EDITORS
CHIEF EDITOR
Sukhikh Gennadii Tikhonovich
Academician of the Russian Academy of Medical Sciences, V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Moscow
CHIEF EDITOR
Kurtser Mark Arkadievich
Academician of the Russian Academy of Sciences, MD, Professor, Head of the Obstetrics and Gynecology Subdepartment of the Pediatric Department, N.I. Pirogov Russian National Scientific Research Medical University, Ministry of Health of the Russian Federation
CHIEF EDITOR
Radzinsky Viktor Evseevich
Corresponding Member of the Russian Academy of Sciences, MD, Professor, Head of the Subdepartment of Obstetrics and Gynecology with a Course of Perinatology of the Medical Department in the Russian People?s Friendship University

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