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3 . 2020

Vitamin D and its receptors in the pathogenesis of obstetric complications: a modern view of the problem

Abstract

Vitamin D deficiency is widespread throughout the world, including among pregnant women. Recently, there has been a sharp increase in interest in the "hormone D" - calcitriol and its receptors (VDR) as risk factors for the development of a number of obstetric complications. The review is devoted to calcitriol - dependent mechanisms of the pathogenesis of obstetric complications such as spontaneous abortion, preterm birth, intrauterine growth restriction, preeclampsia, perinatal infections and gestational diabetes.

Keywords:vitamin D, cholecal-ciferol, pregnancy, preterm birth, preeclampsia, miscarriage, reproductive loss

Funding. The study had no sponsor support.

Conflict of interests. The authors declare no conflict of interests.

For citation: Ramazanova F.U., Khamoshina M.B., Gigani O.O., Tulupova M.S. Vitamin D and its receptors in the pathogenesis of obstetric complications: a modern view of the problem. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2020; 8 (3): 75-80. DOI: 10.24411/2303-9698-2020-13011 (in Russian)

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CHIEF EDITORS
CHIEF EDITOR
Sukhikh Gennadii Tikhonovich
Academician of the Russian Academy of Medical Sciences, V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Moscow
CHIEF EDITOR
Kurtser Mark Arkadievich
Academician of the Russian Academy of Sciences, MD, Professor, Head of the Obstetrics and Gynecology Subdepartment of the Pediatric Department, N.I. Pirogov Russian National Scientific Research Medical University, Ministry of Health of the Russian Federation
CHIEF EDITOR
Radzinsky Viktor Evseevich
Corresponding Member of the Russian Academy of Sciences, MD, Professor, Head of the Subdepartment of Obstetrics and Gynecology with a Course of Perinatology of the Medical Department in the Russian People?s Friendship University

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