Morphological and immunohistochemical features of endometrial polyps in different ages groups

• Liana Yu. Bagdasaryan
• Vladislav V. Ponomarev
• Lyudmila G. Dryaeva
• Lyudmila Yu. Karakhalis

Abstract

The important factors in the development of the endometrial polyps are number of mechanisms: the presence of absolute or relative hyperestrogenia and not fully defined role of infection, as well as their influence on each other. The search for pathogenically determined approaches aimed at preventing the recurrence of endometrial polyps is relevant task.

Keywords:endometrial polyp, infection, hormonal abnormalities

References

1. American Association of Gynecologic Laparoscopists. AAGL practice report: practice guidelines for the diagnosis and management of endometrial polyps. J Minim Invasive Gynecol. 2012; 19 (1): 3-10.

2. Lo K.W.K., Yuen P.M. The role of outpatient diagnostic hysteroscopy in identifying anatomic pathology and histopathology in the endometrial cavity. J Am Assoc Gynecol Laparoscop. 2000; 7 (3): 381-5.

3. Svirsky R., Smorgick N., Rozowski U., et al. Can we rely on blind endometrial biopsy for detection of focal intrauterine pathology? Am J Obstet Gynecol. 2008; 199 (2): 115.e1-115.e3.

4. Bettocchi S., Ceci O., Vicino M., Marello F., Impedovo L., Selvaggi L. Diagnostic inadequacy of dilatation and curettage Fertil Steril. 2001; 75 (4): 803-5.

5. Kalinina, N.M. Chronic endometritis. Approaches to diagnosis and therapy. Consilium Medicum. 2015; 17 (6). (in Russian)

6. Ellinidi V.N., Kalinina, N.M. Immunomorphology of endometrium. Infertility treatment: unresolved problems. Saratov, 2001: 158-62. (in Russian)

7. McClelland R.A., Wilson D., Leake R. et al. A multicenter study into the reliability of steroid receptor immunocytochemical quantification. Eur J Cancer. 1991; 27 (6): 711-5.

8. Gynecology: textbook / edit. by V.E. Radzinsky, А.М Fux. Moscow: GEOTAR-Media, 2014. 1000 p. (in Russian)

9. Gynecology: textbook / ed. by G.M. Savelieva, V.G. Breusenko. Moscow: GEOTAR-Media, 2014. 432 p. (in Russian)

10. Khardikov A.V., Gazaryan M.G., Ivanova O.Y, Luneva I.S. Nonspecific chronicl inflammatory pelvic diseases and perinatal problems. Women's Health and Reproduction: online edition. 2019; 4 (35). (in Russian)

11. Savchenko T.N., Voropaeva E.A., Batiyan T.S., Melnokov A.V., Strygina V.A. State of microbiocenosis and local immunity in postmenopausal patients with endometrial polyps. Doctor.ru. 2011; 9: 33-8. (in Russian)

12. Ovcharuk E.A., Khadartsev K.A., Ovcharuk V.L. Chronic autoimmune endometritis: diagnosis and treatment (brief report). Bulletin of New Medical Technologies (online edition). 2013; 1: 2-198. URL: http://medtsu.tula.ru/VNMT/Bulletin/E2013-1/4589.pdf (in Russian)

13. Nieminen T.T., Gylling A., Abdel-Rahman W.M., et al.] Molecular analysis of endometrial tumorigenesis: importance of complex hyperplasia regardless of atypia. Clin Cancer Res. 2009; 15 (18): 5772-83.

14. Ovcharuk E.A., Khabarov S.V., Hadarceva K.A. Local injection of liposomal emultion “Flamena” in the treatment of chronic endometritis with autoimmune maladjustment. Bulletin of New Medical Technologies. 2018; 25 (3): 87-95. (in Russian)

15. Baranov I.I., Kukarskaya I.I., Karakhalis L.Yu., Sukhanov A.A., Vi-nitsky A.A. Complex approach to pelvic inflammatory diseases treatment. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie [Obstetrics and Gynecology: News, Opinions, Training]. 2018; 4 (22): 65-71. (in Russian)

16. Sukhanov A.A., Karakhalis L.Y., Kukarskaya I.I., Baranov I.I. Multicomponent therapy of patients with inflammatory diseases of the pelvic organs. Akusherstvo i ginekologiya [Obstetrics and Gynecology]. 2018; 12: 125-31. (in Russian)

17. Makhina E.V., Pichigina A.K., Koldasheva E.V., et al. Diagnostic and prognostic significance of evaluation of proliferative activity of endometrial cell populations in hyperplastic and neoplastic processes. Fundamental'nye issledovaniya [Fundamental Research]. 2014; 10 (2): 420-7. (in Russian)

18. Satarov Sh.N., Kogan E.A., Sarkisov S.E., et al. Molecular mechanisms of pathogenesis of endometrial polyps in postmenopause. Akusherstvo i ginekologiya [Obstetrics and Gynecology]. 2013; 6: 17-22. (in Russian)

19. Savelieva G.M., Breusenko V.G., Kareva E.N., et al. Pathogenesis of endometrial polyps in pre- and postmenopausal patients. Expression of estradiol and progesterone receptor genes in their tissue. Akusherstvo i ginekologiya [Obstetrics and Gynecology]. 2015; 3: 33-9. (in Russian)

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)