Surgical management of invasive cervical cancer

• Dmitry L. Ovodenko
• Khabas G.N.
• Makarova Anna S.
• Seregin Alexander A.
• Golitsyna Julia S.
• Ashrafyan Lev A.

Abstract

The aim of the review was to analyze modern literature data on the features of radical operations which were performed using open access and laparoscopy in patients with cervical cancer of various stages.

Material and methods. The review includes data from foreign and domestic articles that were found in elibrary.ru and PubMed databases on the cantus.

Results. Types of invasive cervical cancer surgery are described, and their classifications by the level of parametrectomy and lymph node dissection are represented. The features of laparotomic and laparoscopic operations in patients with locally advanced cervical cancer after neoadjuvant chemotherapy are analyzed.

Conclusion. In early stages of cervical cancer good oncological results of surgical interventions can be achieved with both laparotomic and laparoscopic access techniques. In patients with locally advanced cervical cancer after neoadjuvant chemotherapy, endovideosurgical techniques usage allows to achieve sufficient level of radicality for surgical interventions while maintaining the benefits of minimally invasive access.

Keywords:cervical cancer, Wertheim hysterectomy, laparoscopy

References

1. Ashrafyan L.A.,Antonova I.B. , Basova I.O., IvashinaS.V., Lyustik A.V., Antoshechkina M.A. Possible ways of reorganizing primary health care in gynecology in the light of effective early diagnosis of reproductive system cancer. Opukholi zhenskoy reproduktivnoy sistemy [Tumors of Female Reproductive System]. 2008; 4: 57-63. (in Russian)

2. Ferlay J., Shin H.R., Bray F., Forman D., et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010; 127 (12): 2893-917.

3. Khokhlova S.V., Kolomiets L.A., Kravets O.A., Krikunova L.I., et al. Practical recommendations for drug treatment of cervical cancer. Practical recommendations for the treatment of malignant tumors of the Russian Society of Clinical Oncology. Moscow: RUSSCO, 2016. (in Russian)

4. Eifel P.J. Chemoradiotherapy in the treatment of cervical cancer. Semin Radiat Oncol. 2006; 16 (3): 177-85.

5. Bohman Ya.V. Oncogynecology guideline. St. Petersburg, 2002. (in Russian)

6. Solenova L.G. Second primary malignancies in cancer survivors: epidemiology, role of anticancer therapy. Uspekhi molekulyarnoy onkologii [Advances in Molecular Oncology]. 2016; 3: 30-42. (in Russian)

7. NCCN News. J Natl Compr Cancer Netw. 2017; 15 (1): xxvi-xxvii. (in Russian)

8. Kravets O.A., Kuznetsov V.V., Morkhov K.Yu., Nechushkina V.M., et al. Clinical guidelines for the diagnosis and treatment of cervical cancer. Moscow, 2014. (in Russian)

9. Ungar L., Nechushkina V.M. Why should we perform extended surgeries for cervical cancer? Sibirskiy onkologicheskiy zhurnal [Siberian Oncology Journal]. 2013; 3: 5-13. (in Russian)

10. Vinokurov V.L. Cervical, uterine and ovarian carcinoma: results and perspectives of research conducted at the central research institute of roentgeno-radiology, the ministry of health of the RF. Voprosy onkologii [Oncology Issues]. 2003; 5: 656-62. (in Russian)

11. Gorbunova V. V. Optimization of combined radiation therapy for locally advanced cervical cancer and relapse of ovarian cancer with chemotherapy in therapeutic regimen. Diss. Moscow, 2002. (in Russian)

12. Limbergen V. Scientific-based recommendations for radiotherapy for cervical cancer/ European School of Oncology. Seminar in Red Square "Modern aspects of oncogynecology". Moscow, 2009: 11-27. (in Russian)

13. Kandakova E.Yu., Dzyuba V.V., Vasilyeva T.A. The first experience of multi-component treatment of patients with locally advanced cervical cancer. V All-Russian Congress of Oncogynecologists. Kazan, 2000: 342-4. (in Russian)

14. Panici P.B., Di Donato V., Palaia I., Visentin V.S., et al. Type B versus type C radical hysterectomy after neoadjuvant chemotherapy in locally advanced cervical carcinoma: a propensity-matched analysis. Ann Surg Oncol. 2016; 23 (7): 2176-82.

15. Kolomiets L.A., Churuksaeva O.N. Role of chemotherapy in treatment of locally advanced cervical cancer. Sibirskiy onkologicheskiy zhurnal [Siberian Oncology Journal]. 2006. № 1: 61-3. (in Russian)

16. Moore D.H. Neoadjuvant chemotherapy for cervical cancer. Expert Opin Pharmacother. 2003; 4 (6): 859-67.

17. Wertheim E. The extended abdominal operation for carcinoma uteri (based on 500 operative cases). Am J Obstet Dis Women Child. 1912; 66: 169-232.

18. Kuznetsov V.V., Lebedev A.I., Morkhov A.A. Surgery for invasive cervical cancer. Practical oncogynecology: selected lectures. St. Petersburg, 2008. (in Russian)

19. Piver M.S., Rutledge F., Smith J.P. Five classes of extended hysterectomy for women with cervical cancer. Obstet Gynecol. 1974; 44 (2): 265-72.

20. Ashrafyan L.A., Antonova I.B., Aleshikova O.I., Dobrovolskaya N.Yu. Surgical stage as one of the main components in complex treatment of stage IIb - IIIb cervical cancer Rossiyskiy onkologicheskiy zhurnal [Russian Oncology Journal]. 2007; 3: 21-5. (in Russian)

21. Querleu D., Morrow C.P. Classification of radical hysterectomy. Gynecol Oncol. 2009; 115 (2): 314-5; author reply 315-6.

22. Berlev I.V., Ulrikh E.A., Ibragimov Z.N., Guseinov K.D., Gorod-nova T.V., Korolkova E.N., Trifanov Yu.N., Nekrasova E.A., Saparov A.B., Khadzhimba A.V., Mikaya N.A., Urmancheeva A.F. Indocyanine green (icg) in the detection of sentinel lymph nodes in endometrial and cervix cancer. Voprosy onkologii [Oncology Issues]. 2015; 61 (3): 471-6. (in Russian)

.23. Cibula D., Abu-Rustum N.R. Pelvic lymphadenectomy in cervical cancer - surgical anatomy and proposal for a new classification system. Gynecol Oncol. 2010; 116 (1): 33-7.

24. Cibula D., Ungar L., Svarovsky J., Zivny J., Freitag P. Abdominal radical trachelectomy--technique and experience. Ceska Gynekol. 2005; 70 (2): 117-22.

25. Wang Y.Z., Deng L., Xu H.C., Zhang Y., et al. Laparoscopy versus laparotomy for the management of early stage cervical cancer. BMC Cancer. 2015; 15: 928.

26. Anagnostopoulos A., Mitra S., Decruze B., Macdonald R., et al. Safety and cost considerations during the introduction period of laparoscopic radical hysterectomy. Obstet. Gynecol. Int. 2017. Vol. 2017. Article ID 2103763.

27. Park D.A., Yun J.E., Kim S.W., Lee S.H. Surgical and clinical safety and effectiveness of robot-assisted laparoscopic hysterectomy compared to conventional laparoscopy and laparotomy for cervical cancer: a systematic review and meta-analysis.Eur J Surg Oncol. 2017; 43 (6): 994-1002.

28. Hareyama H., Hada K., Goto K., Watanabe S., et al. Prevalence, classification, and risk factors for postoperative lower extremity lymphedema in women with gynecologic malignancies: a retrospective study. Int J Gynecol Cancer. 2015; 25 (4): 751-7.

29. Berlev I.V., Ulrikh E.A., Korolkova E.N., Ibragimov Z.N., Kashina N.O., Mikhailyuk G.I., Khadzhimba A.V., Urmancheeva A.F. An experience of laparoscopic nerve-sparing radical hysterectomies in treatment for cervical cancer. Voprosy onkologii [Oncology Issues]. 2015; 61 (3): 362-8. (in Russian)

30. Puntambekar S.P., Palep R.J., Puntambekar S.S., Wagh G.N. et al. Laparoscopic total radical hysterectomy by the Pune technique: our experience of 248 cases. J Minim Invasive Gynecol. 2007; 14 (6): 682-9.

31. Landoni F., Maneo A., Zapardiel I., Zanagnolo V., et al. Class I versus class III radical hysterectomy in stage IB1-IIA cervical cancer. A prospective randomized study. Eur J Surg Oncol. 2012; 38 (3): 203-9.

32. Cibula D., Velechovska P., Slama J., Fischerova D., et al. Late morbidity following nerve-sparing radical hysterectomy. Gynecol Oncol. 2010; 116 (3): 506-11.

33. Marin F., Plesca M., Bordea C.I., Voinea S.C., et al. Postoperative surgical complications of lymphadenohysterocolpectomy. J Med Life. 2014; 7 (1): 60-6.

34. Chatkov I.E., Barsukov Yu.A., Atroshchenko A.O., Aliyev V.A. , Kuzmichev D.V., Tamrazov R.I., Gordeyev S.S.. History of laparoscopic surgery. Onkologicheskaya koloproktologiya [Oncological Coloproctology]. 2012; 2: 35-9. (in Russian)

35. Terai Y., Tanaka T., Sasaki H., Kawaguchi H. et al. Total laparoscopic modified radical hysterectomy with lymphadenectomy for endometrial cancer compared with laparotomy. J Obstet Gynaecol Res. 2014; 40 (2): 570-5.

36. Salicru S., Gil-Moreno A., Montero A., Roure M., et al. Laparoscopic radical hysterectomy with pelvic lymphadenectomy in early invasive cervical cancer. J Minim Invasive Gynecol. 2011; 18 (5): 555-68.

37. Reich H. Laparoscopic hysterectomy. Surg Laparosc Endosc. 1992; 2 (1): 85-8.

38. Querleu D., Leblanc E., Castelain B. Laparoscopic pelvic lymphadenectomy in the staging of early carcinoma of the cervix. Am J Obstet Gynecol. 1991; 164 (2): 579-81.

39. Adamyan L.V., Kozachenko A.V. Laparoscopic surgery in oncogynecology. 8th Russian Oncological Congress. Moscow, 2004: 40-2. (in Russian)

41. Nezhat C. Operative endoscopy will replace almost all open procedures. JSLS. 2004; 8 (2): 101-2.

42. Querleu D., Leblanc E., Castelain B., Lanvin D., et al. New therapeutic plans for cancer of the cervix. J. Gynecol. Obstet. Biol. Reprod. (Paris). 2000; 29 (3): 254-7.

43. Spirtos N.M., Schlaerth J.B., Kimball R.E., Leiphart V.M., et al. Laparoscopic radical hysterectomy (type III) with aortic and pelvic lymphadenectomy. Am J Obstet Gynecol. 1996; 174 (6): 1763-7; discussion 1767-8.

44. Hong J.H., Choi J.S., Lee J.H., Eom J.M. et al. Can laparoscopic radical hysterectomy be a standard surgical modality in stage IA2-IIA cervical cancer? Gynecol Oncol. 2012; 127 (1): 102-6.

45. Vizza E., Pellegrino A., Milani R., Fruscio R., et al. Total laparoscopic radical hysterectomy and pelvic lymphadenectomy in locally advanced stage IB2-IIB cervical cancer patients after neoadjuvant chemotherapy. Eur J Surg Oncol. 2011; 37 (4): 364-9.

46. Cai J., Yang L., Dong W., Wang H., et al. Retrospective comparison of laparoscopic versus open radical hysterectomy after neoadjuvant chemotherapy for locally advanced cervical cancer. Int J Gynaecol Obstet. 2016; 132 (1): 29-33.

47. Corrado G., Cutillo G., Saltari M., Mancini E., et al. Surgical and oncological outcome of robotic surgery compared with laparoscopic and abdominal surgery in the management of locally advanced cervical cancer after neoadjuvant chemotherapy. Int J Gynecol Cancer. 2016; 26 (3): 539-46.

48. Backes F.J., Fowler J.M. Hysterectomy for the treatment of gynecologic malignancy. Clin Obstet Gynecol. 2014; 57 (1): 115-27.

49. Mandic A., Golubovic A., Majdevac I. Laparoscopy in gynecologic oncology: a review of literature. Vojnosanit Pregl. 2013; 70 (9): 61-5.

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