Eternal obstetric problems – preeclampsia, preterm delivery

• Devyatova E.A.

Abstract

Actuality: the article reviews a strategy for identification of pregnancies at risk of preeclampsia.

The effective prediction of early preeclampsia potentially improves perinatal outcome. Placental growth factor, soluble fms-like tyrosine kinase-1, and inhibin A role in sin gleton and multiple-gestation pregnancies for pre dicting preeclampsia and small for gestational age newboms is observed. In women with a multiple pregnancy, spontaneous preterm delivery is the leading cause of perinatal morbid ity and mortality. We assessed whether a cervical pessary could effectively prevent poor perinatal outcomes. The role of caesarean section in preterm births, breech presenta tion and twin pregnancies is controversial and lacks good evidencebased guidelines. We reviewed the evidence on the place of caesarean delivery in these important groups.

Keywords:screening for preeclampsia and SGA, vascular endothelial growth factor (VEGF), placental growth factor (PIGF), soluble fms-like tyrosine kinase-l (sFlt-l), inhibin A, soluble endoglin (s-Eng), caesarean, preterm breech, preterm twin delivery, multiple-gestation pregnancies

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